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- 品牌:MedKoo
- 產(chǎn)地:美國(guó)
- 貨號(hào):526260
- cas:909089-13-0
- 發(fā)布日期: 2022-07-20
- 更新日期: 2024-08-12
產(chǎn)地 | 美國(guó) |
品牌 | MedKoo |
貨號(hào) | 526260 |
用途 | This product is for research use only, not for human or veterinary use. |
包裝規(guī)格 | 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; 5.0g; |
CAS編號(hào) | 909089-13-0 |
純度 | >98%% |
是否進(jìn)口 | 是 |
Description: SKL-2001 is a novel agonist of Wnt/β-catenin signaling pathway. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. SKL2001 inhibited proliferation of colon cancer cells cultured in 3D spheroid and induced them accumulation in the G0/G1 phase of the cell cycle with a reduced c-myc level.
Name: SKL2001 free base
CAS#: 909089-13-0
Chemical Formula: C14H14N4O3
Exact Mass: 286.1066
Molecular Weight: 286.291
Elemental Analysis: C, 58.74; H, 4.93; N, 19.57; O, 16.77
Synonym: SKL-2001; SKL 2001; SKL2001; Wnt Agonist II;
IUPAC/Chemical Name: 5-(Furan-2-yl)-N-(3-imidazol-1-ylpropyl)-1,2-oxazole-3-carboxamide
InChi Key: PQXINDBPUDNMPE-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H14N4O3/c19-14(16-4-2-6-18-7-5-15-10-18)11-9-13(21-17-11)12-3-1-8-20-12/h1,3,5,7-10H,2,4,6H2,(H,16,19)
SMILES Code: O=C(C1=NOC(C2=CC=CO2)=C1)NCCCN3C=CN=C3
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001