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- 品牌：MedKoo
- 產(chǎn)地：美國(guó)
- 貨號(hào)：407969
- cas：401600-86-0
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國(guó) |
| 品牌 | MedKoo |
| 貨號(hào) | 407969 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 1.0mg; 5.0mg; 10.0mg; |
| CAS編號(hào) | 401600-86-0 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: STX140 is a bis-sulfamate derivative of the endogenous steroid 2-methoxyestradiol, has shown promising anticancer potency both in vitro and in vivo, with excellent bioavailability. STX140 is efficacious in vitro and in vivo in taxane-resistant breast carcinoma cells. STX140 causes apoptosis via the intrinsic mitochondrial pathway and down-regulate survivin and XIAP expression in ovarian and prostate cancer cells.
Name: STX140
CAS#: 401600-86-0
Chemical Formula: C19H28N2O7S2
Exact Mass: 460.1338
Molecular Weight: 460.56
Elemental Analysis: C, 49.55; H, 6.13; N, 6.08; O, 24.32; S, 13.92
Synonym: STX140; STX-140; STX 140; 2-Methoxyestradiol-3,17-O,O-bis(sulfamate);
IUPAC/Chemical Name: (8R,9S,13S,14S,17S)-2-methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diyl bis(sulfamate)
InChi Key: AQSNIXKAKUZPSI-SSTWWWIQSA-N
InChi Code: InChI=1S/C19H28N2O7S2/c1-19-8-7-12-13(15(19)5-6-18(19)28-30(21,24)25)4-3-11-9-17(27-29(20,22)23)16(26-2)10-14(11)12/h9-10,12-13,15,18H,3-8H2,1-2H3,(H2,20,22,23)(H2,21,24,25)/t12-,13+,15-,18-,19-/m0/s1
SMILES Code: C[C@@]12[C@@H](OS(=O)(N)=O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=C(OC)C(OS(=O)(N)=O)=C4)[C@@]3([H])CC2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
